RMA DelaysOur Admin Portal website is currently experiencing technical difficulties, and it could result in delays with RMAs being processed. We are currently working to resolve these issues. We apologize for the inconvenience.
Join us on August 11th for an ActiGraph webinar hosted by Xtalks:
Oncology Research and Care: Reimagining Digital InnovationRegister Now
Effects of Reducing Sedentary Time on Glucose Metabolism in Pakistani Immigrant Men
- Published on July 23, 2014
Purpose: To examine the association between changes in objectively measured overall physical activity (PA), with changes in fasting and postprandial plasma insulin, C-peptide and glucose concentrations, in type 2 diabetes prone Pakistani immigrant men living in Norway and to examine whether this association is explained by changes in moderate-and-vigorous PA (MVPA) or changes in sedentary time.
Methods: The current study is a secondary cohort analysis on data collected from the Physical activity and minority health study, a randomised controlled trial aimed to increase the PA level, and not sedentary time per se, in a group of sedentary Pakistani immigrant men (n=150). For the present analyses the two groups were merged and a cohort analysis performed. Overall PA (counts per min) and its sub-components, sedentary time and MVPA were measured with accelerometry. Outcome variables were measured after a 2-hour standardised glucose tolerance test.
Results: Change in overall PA was significantly associated with postprandial log transformed plasma insulin ([beta]=-0.002, 95% CI -0.003 to 0.000, P=0.008), C-peptide ([beta]=-2.7, 95% CI -4.9 to -0.5, P=0.01) and glucose concentration ([beta]=-0.006, 95% CI -0.01 to -0.002, P=0.002). Change in sedentary time was significantly and beneficially associated with changes in postprandial log transformed plasma insulin ([beta]=0.002, 95% CI 0.001 to 0.003, P=0.001), C-peptide ([beta]=3.7, 95% CI 1.5 to 6.0, P=0.001) and glucose concentration ([beta]=0.006, 95% CI 0.002 to 0.1, P=0.002) independent of changes in MVPA, waist circumference and other confounders.
Conclusion: Increasing overall PA by reducing sedentary time appears as important as increasing time spent at MVPA in relation to postprandial plasma insulin and glucose levels in diabetes prone immigrant men.