Jul
2011

ActiGraph to help COPD patient research

Re-posted from the ProActive website at http://www.proactivecopd.com/about/news/proactive-newsf/
PROactive selects two activity monitors to support further COPD research

The DynaPort© MoveMonitor© and the ActiGraph GT3X+ are selected for further COPD research in PROactive. A memorandum of understanding has been signed between PROactive and the two companies producing the activity monitors.

After a thorough selection process involving more than 100 patients in 4 European centers the PROactive activity monitor validation team has selected two monitors out of six potentially interesting monitors for further research in COPD. In a first study forty patients wore six activity monitors during one hour while their energy expenditure was assessed using a portable measure of oxygen consumption. In a second study eighty patients wore three to five monitors for 14 days. Energy expenditure (as a measure of physical activity) was estimated with doubly labeled water. The PROactive project team also verified the usability at the patient level. Patients were asked to score the comfort of the monitors and whether these were felt intrusive.

The DynaPort© MoveMonitor© (McRoberts, The Hague, NL) and the ActiGraph GT3X+ monitor (ActiGraph, Pensacola, FL) passed all validation tests and received a good report from the patients. In addition the two companies are willing to provide full support to the PROactive consortium to integrate the outcomes of the monitors in the patient reported outcome instruments.

In the next Work Package (WP4) both activity monitors will be used in 250 patients in combination with a newly developed item list in order to have a comprehensive view of physical activity in patients with COPD. Results of the monitors’ validation studies and of the patients’ usability study will be presented at the international congress of the European Respiratory Society in Amsterdam in September of 2011.

More information on the PROactive consortium www.PROactivecopd.com

More information on the project’s scientific development: Prof Thierry Troosters, KU-Leuven thierry.troosters@med.kuleuven.be

More information on the project in general: Prof Tim Higenbottam, Chiesi Farmaceutici profhigenbottam@btinternet.com

More information on the European Respiratory Society Congress: www.ersnet.org